The Sherpa Pak™ CTS is intended to provide a safe, consistent method for cold ischemic storage and transport of donor hearts to recipients for implantation. The device combines innovative cooling technology with a safe, consistent method for cold ischemic storage and transport of donor hearts to recipients for implantation. The Sherpa Pak™ CTS is intended for transport of hearts within the time frame currently considered as routine medical practice.
The Sherpa Pak™ CTS is indicated for the static hypothermic preservation of hearts during transportation and eventual transplantation into a recipient, using cold storage solutions indicated for use with the heart.
The Paragonix Sherpa™ Cardiac Transport System[1,2]
Currently, the availability of cardiac transplantation is governed by the “ischemic time”, that being, the elapsed time from heart donation to recipient implantation. According to The International Society Of Heart and Lung Transplantation (“ISHLT”) guidelines for the care of heart transplant recipients, the projected ischemic time should not exceed 4 hours,, limiting the distance available to transport a donor heart.
The Paragonix Sherpa™ combines innovative oxygenated perfusion of organs and safe organ storage with the goal of extending ischemic time to 12 hours, significantly altering the transportation range of donor hearts. Paragonix Sherpa™ is designed to be used in conjunction with any of the currently available organ preservation solutions. Paragonix Sherpa™ is fully disposable, eliminating problems associated with maintenance, device transport and contamination.
 This product is not approved for sale.
 Patents issued and pending.
 ISHLT Guidelines for the Care of Heart Transplant Recipients, Task Force 1: Peri-operative Care of the Heart Transplant Recipient (Aug. 4, 2010)
 J Heart Lung Transplant 2001; 20(2):212.
 J Am Coll Cardiol 2004; 43(9):1553-1561.