Improved Clinical Outcomes for Heart Transplant Recipients Announced from International Study on Paragonix SherpaPak® CTS

CAMBRIDGE, MASSACHUSETTS, April 28, 2021 - Paragonix Technologies announced the presentation of the First Report of the GUARDIAN Registry1 at the International Society for Heart and Lung Transplantation 2021 Annual Meeting.  The GUARDIAN study is the…

Continue ReadingImproved Clinical Outcomes for Heart Transplant Recipients Announced from International Study on Paragonix SherpaPak® CTS

Utilization of New Heart Preservation Technology in the Era of New Organ Allocation and Extended Ischemic Times

Funamoto, et al.Journal of Heart and Lung TransplantationApril 2019; Volume 38, Issue 4, S44.https://doi.org/10.1016/j.healun.2020.01.1046Purpose : Current ice bag heart preservation technique is associated with wide fluctuations of organ temperature, resulting in…

Continue ReadingUtilization of New Heart Preservation Technology in the Era of New Organ Allocation and Extended Ischemic Times

Oxygen consumption during oxygenated hypothermic perfusion as a measure of donor organ viability.

Bunegin L, Tolstykh GP, Gelineau JF, Cosimi AB, Anderson LMASAIO Journal2013 Jul-Aug; 59(4):427-32https://www.ncbi.nlm.nih.gov/pubmed/23820283Hypothermic machine perfusion (HMP) for the preservation of kidneys, recovered from extended criteria organ donors (ECDs), presents the opportunity…

Continue ReadingOxygen consumption during oxygenated hypothermic perfusion as a measure of donor organ viability.

Novel portable hypothermic pulsatile perfusion preservation technology: Improved viability and function of rodent and canine kidneys.

A reliable, portable, cost effective device for perfusion preservation of donor organs remains elusive. A portable, organ perfusion device design for hypothermic, machine perfusion (HMP) that successfully supported rodent kidneys for 24 hours was evaluated in canine kidneys.

Continue ReadingNovel portable hypothermic pulsatile perfusion preservation technology: Improved viability and function of rodent and canine kidneys.

Twelve-hour canine heart preservation with a simple, portable hypothermic organ perfusion device.

Cardiac transplantation is limited to an ischemic time of around 6 hours by available preservation solution and technique. Complex organ preservation devices have been developed that extend this time to 24 hours or more, but are clinically impractical. This study evaluates a portable oxygen-driven organ perfusion device weighing approximately 13.5 kg.

Continue ReadingTwelve-hour canine heart preservation with a simple, portable hypothermic organ perfusion device.