Publications

Below is a bibliography of publications about the Paragonix Technologies products and related areas of research.

First Report of the GUARDIAN Registry: An International Consortium Examining the Effect of Controlled Hypothermic Preservation in Heart Transplantation
D.D’Alessandro, J.Philpott, T. Boeve, S. Pham, A. Zuckermann
Presentation at ISHLT 2021 
https://www.jhltonline.org/article/S1053-2498(21)00412-5/abstract

Early Experience with a New Storage Device for Cold Preservation
J. Gökler, P. Angleitner, R. Moayedifar, H. Johann, A. Aliabadi-Zuckermann, G. Laufer, A. Zuckermann.
Poster at ISHLT 2021 
https://www.sciencedirect.com/science/article/abs/pii/S1053249821005866

Longest Storage Period with Static Hypothermic Preservation in Cardiac Transplantation: Initial Experience in the West Coast
B. A. Guenthart, A. Alassar, T. Koyano, S. La Francesca, J. L. Chan, A. Krishnan, J. W. MacArthur, Y. Shudo, W. Hiesinger, Y. Woo.
Poster at ISHLT 2021
https://www.jhltonline.org/article/S1053-2498(21)01319-X/abstract

Effect of Donor Heart Preservation Temperature Monitoring Technology on Primary Graft Dysfunction and Outcomes in Heart Transplantation
A. M. Tutunjian, M. Kawabori, T. Nordan, Y. Zhan, F. Y. Chen, K. G. Warner, H. Rastegar, G. S. Couper
Poster at ISHLT 2021 
https://www.jhltonline.org/article/S1053-2498(21)01320-6/abstract

Use of SherpaPak™ CTS for Organ Transportation during Heart Transplantation: First Clinical Use in United Kingdom and Outcomes
V. Mehta, A. Joshi, J. Hasan1, K. Oommen, P. Callan, S. Shaw, R. V. Venkateswaran
Poster at ISHLT 2021 
https://www.jhltonline.org/article/S1053-2498(21)00585-4/abstract

Utilization of New Heart Preservation Technology in the Era of New Organ Allocation and Extended Ischemic Times
M. Funamoto, C.S. Ong, S.E. Kilmarx, S.S. Li, P.J. Spencer, P. Moonsamy, N. Mohan, E.E. Coglianese, G.D. Lewis
R.N. Pierson, M.A. Villavicencio-Theoduloz, D.A. D’Alessandro
The Journal of Heart and Lung Transplantation, Vol. 39, Issue 4, S136, 2020
DOI: https://doi.org/10.1016/j.healun.2020.01.1046

First Experience with a New Storage Device for Cold Preservation
J. Goekler, A. Zuckermann, P. Angleitner, E. Ceran, P. Kaiser, N. Neuber, J. Horvat, G. Laufer, A. Aliabadi-Zuckermann
The Journal of Heart and Lung Transplantation, Vol. 39, Issue 4, S244, 2020
DOI: https://doi.org/10.1016/j.healun.2020.01.924

Cool Static Storage Preservation and Transportation of Donor Hearts: Introducing New Technologies in Latin America: Paragonix SherpaPak™
A. Ameri, N. Bernal Aragon, E. Giordanino, D. Rubira, R. Ratto, L. Favaloro, R. Favaloro, M. Renedo, D. Absi, A. Bertolotti
Presentation at ISHLT 2020
https://cslide-us.ctimeetingtech.com/ishlt40th/public/share/761

The First Clinical Use of a Novel Cold Storage System of Donor Hearts
N. Naito, M. Funamoto, R. Pierson, M. Villavicencio, W. Riley, G. Lewis, D. D’Alessandro
The Journal of Heart and Lung Transplantation, Vol. 38, Issue 4, S244, 2019
DOI: https://doi.org/10.1016/j.healun.2019.01.093

Innovative cold storage of donor organs using the Paragonix Sherpa Pak ™ devices
S.G. Michel, G.M. LaMuraglia II, M.L.L Madariaga, Lisa M. Anderson
Heart, Lung and Vessels. 2015; 7(3): 246-255.
https://pubmed.ncbi.nlm.nih.gov/26495271/

Preservation of Donor Hearts Using Hypothermic Oxygenated Perfusion
S G Michel, G M La Muraglia, M L Madariaga, J S Titus, M K Selig, E A Farkash, J S Allan, L M Anderson, J C Madsen
Annals of Transplantation, 2014; 19:409-416
DOI: https://doi.org/10.12659/AOT.890797https://www.jhltonline.org/article/S1053-2498(21)00412-5/abstract

COLD INJURY

Organ transport temperature box: multicenter study on transport temperature of organs
D F Horch, T Mehlitz, O Laurich, A Abel, S Reuter, H Pratschke, P Neuhaus, C Wesslau
Transplant Proceedings, Vol. 34, Issue 6, 2002
DOI: https://doi.org/10.1016/s0041-1345(02)03253-0

Are temperatures attained by donor hearts during transport too cold?
P J Hendry, V M Walley, A Koshal, R G Masters, W J Keon
The Journal of Thoracic and Cardiovascular Surgery, Volume 98, Issue 4, 1989
DOI: https://doi.org/10.1016/S0022-5223(19)34352-1

Effect of temperature in long-term preservation of vascular endothelial and smooth muscle function
R Ingemansson, A Budrikis, R Bolys, T Sjöberg, S Steen
The Annals of Thoracic Surgery, Volume 61, Issue 5, 1996
DOI: https://doi.org/10.1016/0003-4975(96)00109-9

Endothelial dysfunction caused by University of Wisconsin preservation solution in the rat heart: The importance of temperature
The Journal of Thoracic and Cardiovascular Surgery, Volume 104, Issue 6, 1992
P Mankad, Z Slavik, M Yacoub
DOI: https://doi.org/10.1016/S0022-5223(19)33892-9

Cardiac Transplantation: The Ideal Myocardial Temperature for Graft Transport
W J Keon, P J Hendry, G C Taichman, G W Mainwood
The Annals of Thoracic Surgery, Volume 46, Issue 3, 1988
DOI: https://doi.org/10.1016/S0003-4975(10)65939-5

Preservation & Transport

Donor heart and lung procurement: A consensus statement
H Copeland, J W Awori Hayanga, A Neyrinck, P MacDonald, G Dellgren, A Bertolotti, T Khuu, F Burrows, J G Copeland, D Gooch, A Hackmann, D Hormuth, C Kirk, V Linacre, H Lyster, S Marasco, D McGiffin, P Nair, A Rahmel, M Sasevich, M Schweiger, A Siddique, T J Snyder, W Stansfield, S Tsui, Y Orr, P Uber, R Venkateswaran, J Kukreja, M Mulligan
The Journal of Heart and Lung Transplantation, Vol. 39, Issue 6, 2020
DOI: https://doi.org/10.1016/j.healun.2020.03.020 

Primary Graft Dysfunction

Report from a consensus conference on primary graft dysfunction after cardiac transplantation
J Kobashigawa, A Zuckermann, P Macdonald, P Leprince, F Esmailian, M Luu, D Mancini, J Patel, R Razi, H Reichenspurner, S Russell, J Segovia, N Smedira, J Stehlik, F Wagner
The Journal of Heart and Lung Transplantation, Vol. 33, Issue 4, 2014
DOI: https://doi.org/10.1016/j.healun.2014.02.027

PREDICTA: A Model to Predict Primary Graft Dysfunction After Adult Heart Transplantation in the United Kingdom
S A Singh, S Das De, S Rushton, C Berry, N Al-Attar
Journal of Cardiac Failure, Vol. 25, Issue 12, 2019
DOI: https://doi.org/10.1016/j.cardfail.2019.07.009

Primary graft dysfunction after heart transplantation: Incidence, trends, and associated risk factors
A Nicoara, D Ruffin, M Cooter, C B Patel, A Thompson, J N Schroder, M A Daneshmand, A F Hernandez, J G Rogers, M V Podgoreanu, M Swaminathan, A Kretzer, M Stafford‐Smith, C A Milano, R R Bartz
American Journal of Transplantation, Vol. 18, Issue 6, 2017
DOI: https://doi.org/10.1111/ajt.14588

Incidence, predictors, and outcomes after severe primary graft dysfunction in pediatric heart transplant recipients
E L Profita, K Gauvreau, P Rycus, R Thiagarajan, T P Singh
The Journal of Heart and Lung Transplantation, Vol. 38, Issue 6, 2019
DOI: https://doi.org/10.1016/j.healun.2019.01.1310