Paragonix KidneyVault™

The Next Generation of Kidney Preservation
The Paragonix KidneyVault™ Portable Renal Perfusion System marks a new chapter in kidney transplantation. This FDA-cleared hypothermic preservation device is equipped to perfuse and monitor a kidney throughout the entire transplant journey.
Doctor holding human heart
SherpaPak
Monitor
Real-time data and tracking of perfusion metrics
Perfusion
Continuous circulation of fluids through the kidney
Standardize
Convenient process to optimize logistics from end-to-end
Kidney Perfusion Like Never Before
Perfusing donor kidneys during transport has become a critical standard in modern transplantation, yet it still presents several challenges. Traditional perfusion machines can often be bulky and difficult to transport, particularly over long distances or during air transport. Furthermore, delays in returning these machines and the allocation of valuable capital equipment throughout the process can create inefficiencies.

Paragonix has transformed this process with the KidneyVault Portable Renal Perfusion System, an FDA-cleared, portable perfusion device. Specifically designed for convenience and ease of transport, KidneyVault ensures safe and effective kidney preservation throughout transit. With real-time data monitoring and Paragonix’s proprietary SherpaCool® phase-change technology, it maintains optimal temperatures between 4-8ºC, ensuring the kidney remains in optimal conditions. KidneyVault offers a reliable, streamlined solution to modernize kidney transport, enhancing both the efficiency of transplant teams and the outcomes for recipients.
Caution: Federal (US) law restricts this device to sale by or on the order of a licensed health care practitioner. Please refer to Instructions for Use for full prescribing information. Cleared indication is for 24 hour use. Patents issued and pending. See legal page for more information.
Technological Advantage of Advanced Organ Preservation
Traditional Ice Storage
  • Uses commercial-grade coolers unregulated by the FDA
  • Exposes the the donor kidney(s) to an unmonitored environment of 0°C ice
  • Kidney tissue is exposed to uneven cooling, potentially risking freezing injury
  • Unpredictable temperature reductions within the ice cooler are not monitored during transport
Paragonix KidneyVault
  • An FDA-cleared preservation device intended to actively protect, monitor, and perfuse donor kidney in transit
  • Validated to maintain a consistent thermal environment
  • Utilizes SherpaCool® phase-change technology to prevent exposure to excessive temperature reduction
  • Continuously perfuses donor kidneys' throughout the journey
  • Records live temperature, location, and key perfusion metrics such as renal flow, pressure, and resistance
Envision a future where any donor kidney can be delivered on pump
Key Features
1
Kidney Rest
Inner Canister components support the kidney's position by safely enclosing it between a slope and a structured retainer
2
Portable Renal Perfusion
End-to-end pulsatile hypothermic machine perfusion available throughout the transplant journey
3
Nested Canister System
Pressure-controlled, leak-proof rigid canister safeguards and cools the kidney evenly
4
SherpaCool Technology
Proprietary phase-change cooling formula that maintains optimal temperature conditions without the use of 0ºC ice
5
Rigid Outer Shell
Lightweight shipper system is validated to maintain a consistent thermal environment
6
Monitor and Data Transmission
Access instant preservation location, temperature, pressure, flow and resistance throughout the journey from end-to-end
Follow your transplant’s journey from beginning to end
The Paragonix App and Web Portal allows transplant teams to coordinate case logistics in a centralized, secure platform designed specifically for use in a real-world setting.
Learn More About Our Digital Services
Paragonix App

Important Safety Information

Indications for Use
The Paragonix KidneyVault Portable Renal Perfusion System is intended to be used for the pulsatile hypothermic machine perfusion of kidneys for the preservation, transportation, and eventual transplantation into a recipient using cold storage solutions indicated for use with this organ.

The Paragonix KidneyVault Portable Renal Perfusion System can maintain the donor organ storage temperature between 4°C and 8°C through 24 hours.

Donor kidneys exceeding clinically accepted hypothermic preservation times should be evaluated by the transplant surgeon to determine transplantability in accordance with accepted clinical guidelines and in the best medical interest of the intended recipient.
View Product Training Resources
Access training videos on the Paragonix KidneyVault™, and other products, by simply following the link below. These videos are designed to guide you through key features and processes. Available anytime, anywhere for your convenience.
Request more information about our contributions to advancing donor organ transplantation.
Contact us today
Contact us today
Paragonix Technologies is committed to protecting and respecting your privacy, and we’ll only use your personal information to administer your account and to provide the products and services you requested from us. From time to time, we would like to contact you about our products and services, as well as other content that may be of interest to you. If you consent to us contacting you for this purpose, please check the appropriate box below. You can unsubscribe from these communications at any time. For more information on our privacy practices, and how we are committed to protecting and respecting your privacy, please review our Privacy Policy.
By clicking submit below, you consent to allow Paragonix Technologies to store and process the personal information submitted above to provide you the content requested.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.