Paragonix LUNGguard™
Donor Lung Preservation System
Delivering a New Standard in Lung Preservation. Paragonix LUNGguard™ provides a sterile and temperature controlled environment for organs traveling between operating rooms. The product is designed to be easy-to-use in stressful, clinically demanding environments where there is no room for mistakes.
Paragonix LUNGguard™
Donor Lung Preservation System
Delivering a New Standard in Lung Preservation. Paragonix LUNGguard™ provides a sterile and temperature controlled environment for organs traveling between operating rooms. The product is designed to be easy-to-use in stressful, clinically demanding environments where there is no room for mistakes.
Paragonix LUNGguard™
Donor Lung Preservation System
Delivering a New Standard in Lung Preservation. Paragonix LUNGguard™ provides a sterile and temperature controlled environment for organs traveling between operating rooms. The product is designed to be easy-to-use in stressful, clinically demanding environments where there is no room for mistakes.
Move on from Ice and Unpredictable Results with the LUNGguard Donor Lung Preservation System
The Paragonix LUNGguard™ Donor Lung Preservation System is an FDA cleared and CE marked preservation device for donor lung transportation.
Paragonix LUNGguard™ Donor Lung Preservation system brings the award-winning technology of the Paragonix SherpaPak™ CTS to the world of lung transplantation. The first-of-its-kind preservation method is a major advancement over the current ice and cooler practice used today.
The LUNGguard incorporates the Paragonix proprietary cooling technology to ensure thermal protection for up to 40 hours for all donor lungs while providing a rigid and protective structure for physical safety.
All these features are offered alongside a state-of-the-art app that connects to the LUNGguard via bluetooth for on-the-go monitoring.
Caution: Federal (US) law restricts this device to sale by or in the order of a licensed health care practitioner. Please refer to Instructions for Use for full prescribing information. Cleared indication is for 8-hour use. Patents issued and pending. See Indications For Use for more information.
Predictable, Repeatable, Measurable.
Based on proven cardiac preservation system
architecture.
More control over organ preservation environment
Connectivity and data reporting for the entire transplant team
Standardization of protocols and process
Advancing Lung Preservation
The endothelium of the lung is an extremely vulnerable tissue. Outside of the body, cells once safeguarded by protective homeostatic conditions are suddenly exposed to a highly variable environment. This change can cause harm to such an important layer of tissue.
Current best practices, presented by Mushi et al, point out that, “maintaining viability of the lungs depends on several preservation factors including… storage temperature, mode of transportation, and ischemic times.”1
The International Society for Heart and Lung Transplantation has published a consensus statement that warns to, “avoid direct contact of ice on the lungs as it can cause tissue injury”.2
It’s been published that donor lungs may be at risk of injury from:
- Low temperatures, especially those below 2° C
- Recommended storage temperature is between 4-8°C
- Protracted cold ischemia
- Physical trauma incurred during retrieval, transportation, and transplantation
Want to learn more about the Lung Transplant Foundation and their recipient/caregiver mentorship program?
A Well Documented Need
The need for this device has never been greater. We sought out a collaboration with Paragonix because we saw first-hand the significant challenges in lung transplantation and just how impactful this technology could be.
GUARDIAN-LUNG REGISTRY
Advancing the Science of Preservation
Paragonix is committed to improving the science and understanding of organ preservation and is leading the novel GUARDIAN Study to enhance understanding of the impact of advanced preservation.
Physicians from around the world are publishing their experiences with advanced preservation in clinical research journals.
Indications for Use
The Paragonix LUNGguard™ (LUNGguard™) is intended to be used for the static hypothermic preservation of lungs during transportation and eventual transplantation into a recipient using cold storage solutions indicated for use with the lungs.
The intended organ storage time for LUNGguard™ is up to 8 hours.
Donor lungs exceeding clinically accepted static hypothermic preservation times should be evaluated by the transplant surgeon to determine transplantability in accordance with accepted clinical guidelines and in the best medical interest of the intended recipient.
Note: Partial lungs can be transported via LUNGguard™ by packaging lungs per institutional protocol and UNOS guidelines.
