Abstracts and scientific sessions presented at the 2026 ISHLT Annual Meeting will highlight the growing clinical evidence demonstrating the positive post-transplant impact of Paragonix's advanced organ preservation devices on patient outcomes.

• Paragonix Technologies will feature oral presentations and poster sessions at ISHLT 2026, showcasing clinical data related to its heart and lung preservation devices.
• The extensive research being presented underscores Paragonix’s continued commitment to evidenced-based medicine in the advancement of organ preservation technologies and the impact on transplant outcomes.
• Paragonix will host two industry symposiums at the meeting: “A Higher Standard: Modern Innovations Elevating Lung Preservation” and “Quantifying Innovation: The Measurable Impact of Advanced Heart Preservation”.

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WALTHAM, Mass., April 01, 2026 – Paragonix Technologies, Inc., a pioneer in organ transplant technologies and services, is honored to announce the upcoming presentation of new clinical data supporting the use of its FDA-cleared and CE-marked controlled hypothermic preservation devices and transplant services. The data will be presented by a multi-center panel of clinical investigators representing the GUARDIAN Clinical Registries and will compare and analyze real-world post-transplant patient outcomes at the 46^th ISHLT Annual Meeting and Scientific Sessions, held April 22-25, 2026, at the Metro Toronto Convention Centre in Toronto, Canada.

Clinical investigators will share data and research related to Paragonix heart and lung devices (SherpaPak^® Cardiac Transport System, BAROguard^® Donor Lung Preservation System, and LUNGguard^® Donor Lung Preservation System) in three oral presentations, one mini-oral presentation, and seven posters throughout the conference, including:

Poster Presentations:

• Impact of Controlled Hypothermic Preservation of Donor Hearts on Post-Transplant Costs in the First Year
  • April 22, 2026, 6:01 PM - 7:00 PM - Poster Hall
• Outcomes with Extended Criteria Donor Hearts When Preserved at 4-8°C Compared to Normothermic Preservation
  • April 22, 2026, 6:01 PM - 7:00 PM - Poster Hall
• Outcomes of DCD Hearts Preserved at 4-8°C Following TA-NRP Compared to Normothermic Machine Perfusion
  • April 22, 2026, 6:01 PM - 7:00 PM - Poster Hall
• Use of Advanced Organ Preservation at 4-8°C in Pediatric Heart Transplants with Single Ventricle Physiology
  • April 22, 2026, 6:01 PM - 7:00 PM - Poster Hall
• Does Sex Matter? Post-Lung Transplant Outcomes in Females vs Males
  • April 23, 2026, 4:31 PM - 5:30 PM – Poster Hall
• Impact of Composite Textbook Outcomes on Late Post-transplant Outcomes and Survival
  • April 24, 2026, 4:31 PM - 5:30 PM - Poster Hall
• Use of Controlled Hypothermic Lung Preservation to Optimize Outcomes in Older Recipients
  • April 24, 2026, 4:31 PM - 5:30 PM - Poster Hall

Oral Presentations:

• Lung Transplant Outcomes Stratified by Temperature: Impact on Rejection
  • April 23, 2026, 3:37 PM - 3:45 PM - Hall F+G
• Long-Term Impact of Time Shifting Transplants Using Controlled Hypothermic Lung Preservation
  • April 25, 2026, 8:25 AM - 8:33 AM - Room 714-716
• Association of Controlled Moderate Hypothermic Donor Heart Preservation with Subsequent Allograft Rejection and Non-invasive Surveillance Testing
  • April 25, 2026, 12:58 PM - 1:06 PM - Room 801 A+B

Mini-Oral Presentation:

• Advantages of Adding Controlled Airway Pressure to Hypothermic Lung Preservation
  • April 23, 2026, 5:25 PM - 5:29 PM - Room 718-A

Additionally, Paragonix will be hosting two industry symposiums:

• Lung Symposium - A Higher Standard: Modern Innovations Elevating Lung Preservation
  • Wednesday, April 22^nd, 11:45 am - 12:45 pm - Room 701
• Heart Symposium - Quantifying Innovation: The Measurable Impact of Advanced Heart Preservation
  • Thursday, April 23^rd, 11:45 am - 12:45 pm - Room 701

Both symposium events will feature panels of leading surgeons and investigators from the GUARDIAN Registries as they explore the scientific foundation of advanced organ preservation and examine the associated impact on patient outcomes.

“The breadth of data being shared at this year’s meeting reflects the meaningful progress our field continues to make in organ preservation and transplantation,” said Dr. Lisa Anderson, PhD, President of Paragonix. “We’re proud to support and collaborate with leading investigators whose research is helping to strengthen the clinical foundation for innovation and raise the bar for patient care worldwide.”

To visit the Paragonix Technologies exhibit and meet members of the team at ISHLT, visit booth #712. For more information about Paragonix, visit www.paragonix.com.

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